WHAT IS CBD
CBD (cannabidiol) is the second-most-abundant cannabinoid in cannabis, and the most thoroughly researched non-psychoactive cannabinoid. Chemical formula C₂₁H₃₀O₂.
CBD does not bind strongly to CB1 receptors, so it does not produce the psychoactive "high" associated with THC. Instead, CBD acts as a negative allosteric modulator of CB1, moderating THC’s effects when both are present — which is one mechanism behind the "entourage effect".
Beyond the ECS, CBD interacts with serotonin (5-HT1A), adenosine, and TRPV1 receptors, which is the pharmacological basis for ongoing research into CBD’s effects on anxiety, sleep, seizures, and inflammation.
RESEARCH + APPLICATIONS
Epilepsy — Epidiolex (CBD) is FDA-approved for treatment-resistant pediatric epilepsy (Lennox-Gastaut and Dravet syndromes). This is the only FDA-approved cannabinoid medication.
Anxiety — Multiple clinical trials show CBD reduces anxiety symptoms at doses of 300–600mg, particularly for social anxiety disorder. Research is ongoing.
Sleep — CBD’s anxiolytic effect can support sleep onset for stress-related insomnia. Direct sedative effects are weak.
Inflammation — CBD shows anti-inflammatory effects in preclinical research; clinical translation is preliminary.
Pain — Mixed evidence; CBD may reduce neuropathic pain but is generally less effective than THC for cancer or chronic pain.
PRODUCTS
CBD isolate — 99%+ pure CBD, no other cannabinoids or terpenes. Used in precise-dose products.
Broad spectrum — CBD + minor cannabinoids + terpenes, but THC removed. Entourage effect without psychoactivity.
Full spectrum — CBD + all cannabinoids + terpenes including trace THC (under 0.3%). Maximum entourage effect.
CBD-rich flower — Cannabis cultivars bred for high CBD (8–20%) and low THC (under 1%). Smokable, non-psychoactive.
